Resolvin E4 from CAYMAN CHEMICAL COMPANY

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Product NameResolvin E4
DescriptionAn SPM; produced from EPA by 15-LO via 15(S)-HpEPE and 15S-hydroxy, 5S-HpEPE intermediates in vitro and by isolated human M2 macrophages or PMN neutrophils under normoxic or hypoxic conditions; enhanced synthesis in M2 macrophage and neutrophil co-cultures, indicating transcellular biosynthesis by a potential 15-LO and 5-LO mechanism; has been found in mouse inflammatory exudates; increases efferocytosis of apoptotic neutrophils or sRBCs by human M2 macrophages under hypoxic conditions in vitro; inhibits zymosan A- and thrombin-induced increases in inflammatory exudate neutrophil infiltration in a mouse model of hemorrhagic peritonitis at 100 ng/animal; increases inflammatory exudate macrophage infiltration and efferocytosis of apoptotic neutrophils and/or RBCs in the same model
Size100 µg
Concentrationn/a
Applicationsn/a
Other NamesRvE4
Gene, Accession, CAS #CAS: 1781227-87-9
Catalog #29590-100
Price$903
Order / More InfoResolvin E4 from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com

http://www.caymanchem.com

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