RS 102221 (hydrochloride) from CAYMAN CHEMICAL COMPANY
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| Product Name | RS 102221 (hydrochloride) |
| Description | A 5-HT2C receptor antagonist; binds to 5-HT2C receptors (Ki = 3.8 nM for the recombinant human receptor) and is selective for 5-HT2C receptors over 5-HT2A and 5-HT2B receptors (Kis = 1,122.02 and 812.83 nM, respectively), as well as a panel of additional neurotransmitter receptors and ion channels (Kis = ≥316.23 nM for all); inhibits 5-HT-induced increases in the extracellular media acidification rate of CHO-K1 cells expressing human 5-HT2C receptors (pA2 = 8.1); increases food intake and weight gain in rats at 2 mg/kg; increases the time spent in the light compartment in the light-dark exploration test in mice at 2 mg/kg; reduces prepulse inhibition of the startle reflex in mice at 1 mg/kg |
| Size | 1 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 185376-97-0 RS102221 5HT HT-2C HT-2-C HT2-C A B CHOK1 CHO-K-1 CHO-K-1 CHOK-1 pA-2 neuro transmitter extra cellular |
| Gene, Accession, CAS # | CAS: 187397-18-8 |
| Catalog # | 31543-1 |
| Price | $61.00 |
| Order / More Info | RS 102221 (hydrochloride) from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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