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Product Name | Tat-βsyn-degron (trifluoroacetate salt) |
Description | An α-synuclein knockdown peptide; binds to recombinant α-synuclein in a peptide-protein binding assay and reduces α-synuclein levels in primary rat cortical neuron cultures; reduces brain α-synuclein levels in M38 transgenic mice that overexpress human A53T mutant α-synuclein at 40 mg/kg; reduces phosphorylated α-synuclein levels in the substantia nigra and the pons, as well as neuroinflammation in a mouse model of spreading synucleinopathy; protects against dopaminergic neuron loss and rescues motor deficits in a mouse model of MPTP-induced Parkinson's disease at 6 µmol/kg, i.p. |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 2816095-52-8 HIV1 MG-132 M-38 A53-T A-53T neuro-inflammation |
Gene, Accession, CAS # | n/a |
Catalog # | 37442-1 |
Price | $30.00 |
Order / More Info | Tat-βsyn-degron (trifluoroacetate salt) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |