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Product Name | 12(S)-HEPE |
Description | 12(S)-HEPE is a monohydroxy fatty acid synthesized from EPA by the action of 12-LO. Unstimulated neutrophils metabolize 12(S)-HEPE to 12(S),20-diHEPE, whereas stimulated neutrophils produce 5(S),12(S)-HEPE via the 5-lipoxygenase pathway.{6402} The competitive action of 12(S)-HEPE with arachidonic acid as a substrate for 5-LO in the formation of leukotrienes may provide a basis for the anti-inflammatory potential of ω-3 fatty acids. |
Size | 25 µg |
Concentration | n/a |
Applications | n/a |
Other Names | hydroxy fatty acids EPA 12S-HEPEs 12(S)-HEPEs 12-HEPEs eicosapentaenoic 12(S)HEPEs 12-lipoxygenases 12-LOs |
Gene, Accession, CAS # | CAS: 116180-17-7 |
Catalog # | 32550-25 |
Price | $153.00 |
Order / More Info | 12(S)-HEPE from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |