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Product Name | 3,5-Dinitrocatechol |
Description | A potent COMT inhibitor (IC50 = 12 nM); selective for COMT over tyrosine hydroxylase, dopamine β-hydroxylase, dopamine decarboxylase, MAO-A, and MAO-B (IC50s = >14 µM for all); reduces 3-OMD levels in rat serum when administered in combination with L-DOPA and carbidopa compared with control animals receiving only L-DOPA and carbidopa at 30 mg/kg; chronic administration induces COMT-dependent thermal hyperalgesia and increases preference for dark in a light/dark preference test in rats at 15 mg/kg per day for seven days |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | OR-486 |
Gene, Accession, CAS # | CAS: 7659-29-2 |
Catalog # | 29180-5 |
Price | $109.00 |
Order / More Info | 3,5-Dinitrocatechol from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |