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Product Name | AA-861 |
Description | A 5-LO inhibitor (IC50 = 0.8 µM); >100-fold selective for 5-LO over 12-LO and COX; inhibits A23187-induced production of 5-HETE and LTB4 (IC50s = 0.03 and 0.08 µM, respectively) in isolated rat peritoneal macrophages; reduces carrageenan-induced paw edema, pleurisy, and cell infiltration in rats at 80 mg/kg; reduces ovalbumin-induced bronchoconstriction in an ovalbumin-sensitized guinea pig model of experimental allergic asthma at 20 mg/kg |
Size | 500 µg |
Concentration | n/a |
Applications | n/a |
Other Names | A-61589|Docebenone |
Gene, Accession, CAS # | CAS: 80809-81-0 |
Catalog # | 13263-500 |
Price | $166.00 |
Order / More Info | AA-861 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |