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Product Name | Carbamazepine |
Description | A sodium channel inhibitor; preferentially inhibits inactivated Nav1.7 and Nav1.3 channels (IC50s = 406 and 900 µM, respectively) over resting (closed) Nav1.7 and Nav1.3 channels in whole-cell patch-clamp assays using HEK293 cells (IC50s = 1,584 and 2,464 µM, respectively); inhibits sodium currents in a rat sciatic nerve patch-clamp assay ex vivo at 100 µM; reduces dopamine levels in the striatum and hippocampus, as well as L-DOPA levels in the striatum, in rats at 100 mg/kg; reduces amphetamine-induced hyperactivity in mice at 0.5% w/w in the diet; reduces immobility time in the forced swim test in mice at 0.75% w/w in the diet |
Size | 10 g |
Concentration | n/a |
Applications | n/a |
Other Names | CBZ|NSC 169864 |
Gene, Accession, CAS # | CAS: 298-46-4 |
Catalog # | 15422-10 |
Price | $41.00 |
Order / More Info | Carbamazepine from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |