BMS 502 from CAYMAN CHEMICAL COMPANY
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| Product Name | BMS 502 |
| Description | An inhibitor of DGK-α, DGK-ζ, and DGK-ι; (IC50s = 0.0046, 0.0021, and 0.0026 µM, respectively); selective for these DGKs over DGK-β, DGK-γ, and DGK-κ (IC50s = 1, 0.68, and 4.6 µM, respectively); increases IFN-γ levels and ERK phosphorylation in isolated human whole blood (EC50s = 0.28 and 0.52 µM, respectively); increases the proliferation of CD8+ T cells (EC50 = 0.065 µM), which express DGK-α and DGK-ζ but not DGK-ι; increases the frequency of CD69+ CD8+ T cells in combination with SIINFEKL in OT I mice |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | BMS502 DGKβ DGKγ DGK CD8 CD69 Tcell |
| Gene, Accession, CAS # | CAS: 2407854-18-4 |
| Catalog # | 39303-5 |
| Price | $96.00 |
| Order / More Info | BMS 502 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY