Edit |   |
---|---|
Product Name | BI-847325 |
Description | A selective dual MEK/Aurora kinase inhibitor (IC50s = 3, 25, 15, 25, and 4 nM for X. laevis Aurora B, human Aurora A and Aurora C, and human MEK1 and MEK2, respectively); inhibits the growth and survival of both treatment-naive and drug-resistant melanoma both in vitro and in vivo, decreasing the expression of MEK and Mcl-1 while increasing the expression of pro-apoptotic protein Bim |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | BI847325 MEK/aurora mek aurora kinase |
Gene, Accession, CAS # | CAS: 1207293-36-4 |
Catalog # | 18301-1 |
Price | $73.00 |
Order / More Info | BI-847325 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |