Obeldesivir from CAYMAN CHEMICAL COMPANY
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| Product Name | Obeldesivir |
| Description | An antiviral nucleoside analog and a prodrug form of GS-441524; inhibits the replication of SARS-CoV-2 and SARS-CoV-2 βeta, Gamma, or Omicron variants in infected Vero E6 cells (EC50s = 1.36, 1.127, 0.349, and 0.106 µM, respectively) without inducing cytotoxicity (CC50 = 128 µM); reduces nucleocapsid gRNA copy number and nucleocapsid sgRNA levels in the lungs of, and decreases lung damage in, a KI-hACE2 mouse model of SARS-CoV-2 infection at 250 or 500 mg/kg per day; reduces the levels of S protein in the lungs of, as well as decreases PFUs in lung tissues, reduces lung and spleen inflammation, and prevents viral infection-induced death in, a K18-hACE2 mouse model of SARS-CoV-2 infection at 100 or 250 mg/kg per day |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | ATV006|GS-5245 |
| Gene, Accession, CAS # | CAS: 2647441-36-7 |
| Catalog # | 40404-10 |
| Price | $455.00 |
| Order / More Info | Obeldesivir from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY