CPI-1189 from CAYMAN CHEMICAL COMPANY
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| Product Name | CPI-1189 |
| Description | A benzamide; inhibits phosphorylation of p38 MAPK in IL-1β-stimulated primary rat astrocytes by 70 to 80% at 10-300 nM; decreases TNF-α-induced apoptosis in the corpus callosum and septum, but not in the neocortex or basal ganglia, as well as reduces TNF-α-induced decreases in GFAP levels in isolated rat brain slices at 20 mg/kg per day; decreases the latency to find the platform in the Morris water maze, indicating reversal of memory deficits, induced by TNF-α in a rat model of AIDS dementia at 20 mg/kg per day; reduces crypt loss and decreases the number of ulcers and inflammatory cells in colonic lesions in mouse models of colitis induced by TNBS or DSS at 30 mg/kg per day |
| Size | 100 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 210475-67-5 CPI-1189 antiinflammatory neuro-protective IL1β TNFα |
| Gene, Accession, CAS # | CAS: 183619-38-7 |
| Catalog # | 29187-100 |
| Price | $98.00 |
| Order / More Info | CPI-1189 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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