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Product Name | Satratoxin G |
Description | A macrocyclic trichothecene mycotoxin; induces cleavage of caspase-3 and PARP in HL-60 cells at 40 nM; cytotoxic to HepG2, Hep-2, Caco-2, A204, U937, and Jurkat cells (IC50s = 2.2-9.7 ng/ml); intranasal administration induces apoptosis of olfactory sensory neurons in olfactory epithelium and ethmoid turbinate expression of the genes encoding IL-1α, IL-1β, IL-6, TNF-α, and MIP-2 in mice at 500 µg/kg; induces lethality in 4 week-old male mice (LD50 = 1.23 mg/kg, i.p.) |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Stachybotrys HL60 Hep-G2 Hep2 Caco2 A-204 U-937 IL1α IL1β IL6 TNFα MIP2 |
Gene, Accession, CAS # | CAS: 53126-63-9 |
Catalog # | 9003415-5 |
Price | $1,024.00 |
Order / More Info | Satratoxin G from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |