Safinamide (mesylate) from CAYMAN CHEMICAL COMPANY
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| Product Name | Safinamide (mesylate) |
| Description | An inhibitor of MAO-B (IC50 = ~0.1 µM); selective for MAO-B over MAO-A (IC50 = >10 µM); inhibits radioligand binding to sodium channel binding site 2, sigma-1, and sigma-2 receptors in rat brain membranes (IC50s = 8.2, 0.019, and 1.59 µM, respectively); inhibits high voltage-activated calcium currents and depolarization-induced tetrodotoxin-sensitive fast sodium currents in rat hippocampal neurons; inhibits veratrine-induced glutamate release in rat hippocampal slices (IC50 = 56 µM); inhibits maximal electroshock-induced tonic extension seizures in mice and rats (ED50s = 8 and 11.8 mg/kg, p.o.) as well as maximal seizures induced by bicuculline, picrotoxin, 3-mercaptopropionic acid, and strychnine in mice (ED50s = 26.9, 60.6, 21.5, and 104.1 mg/kg, p.o., respectively) |
| Size | 50 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | EMD 1195686|FCE 26743|NW-1015|PNU-151774E |
| Gene, Accession, CAS # | CAS: 202825-46-5 |
| Catalog # | 21546-50 |
| Price | $507.00 |
| Order / More Info | Safinamide (mesylate) from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY