NSC 146109 (hydrochloride) from CAYMAN CHEMICAL COMPANY
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| Product Name | NSC 146109 (hydrochloride) |
| Description | An activator of p53; increases expression of p53 and the p53 target DR5 in wild-type and p53-knockout HCT116 colon adenocarcinoma cells; selective for p53, having no effect on p73 expression in HCT116 cells (2 µM); increases p53 expression, decreases expression of the p53 suppressor MDMX, and reduces viability in a panel of breast cancer cell lines (0.5 µM); reduces growth of AMC-HN9 HNC cells in vitro and in vivo when administered alone or in combination with cisplatin in a mouse xenograft model (70 mg/kg) |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | XI-011 |
| Gene, Accession, CAS # | CAS: 59474-01-0 |
| Catalog # | 16430-10 |
| Price | $138.00 |
| Order / More Info | NSC 146109 (hydrochloride) from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY