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Product Name | ELOVL1-27 |
Description | An inhibitor of ELOVL1 (IC50 = 900 nM); inhibits LPC(C26:0) synthesis in HEK293 cells (IC50 = 13 nM), as well as in primary fibroblasts isolated from patients with CALD or AMN (IC50s = 15-43 nM); reduces blood LPC(C26:0) levels in wild-type mice and rats; reduces CNS levels of LPC(C26:0) in an ABCD1-/- mouse model of ALD at 1 or 10 mg/kg per day for at least three months |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | ELOVL127 ELOVL-1 HEK-293 ABCD-1 |
Gene, Accession, CAS # | CAS: 2227482-41-7 |
Catalog # | 35323-25 |
Price | $1,667.00 |
Order / More Info | ELOVL1-27 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |