Edit |   |
---|---|
Product Name | Tepoxalin |
Description | A dual inhibitor of COX and 5-LO (IC50s = 2.84 and 0.15 µM, respectively, in RBL-1 cell lysates); inhibits the activity of 12-, but not 15-, LO (IC50s = 4.45 and 146.6 µM for the human platelet and rabbit reticulocyte enzymes, respectively); reduces A23187-induced TXB2 and LTB4 production in human PBMCs (IC50s = 0.01 and 0.07 µM, respectively) and decreases epinephrine-induced platelet aggregation in human PRP (IC50 = 0.045 µM); inhibits paw swelling in a rat model of adjuvant-induced arthritis (ED50 = 3.5 mg/kg) |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | ORF 20485|RWJ 20485 |
Gene, Accession, CAS # | CAS: 103475-41-8 |
Catalog # | 34849-1 |
Price | $37.00 |
Order / More Info | Tepoxalin from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |