Tepoxalin from CAYMAN CHEMICAL COMPANY

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Product NameTepoxalin
DescriptionA dual inhibitor of COX and 5-LO (IC50s = 2.84 and 0.15 µM, respectively, in RBL-1 cell lysates); inhibits the activity of 12-, but not 15-, LO (IC50s = 4.45 and 146.6 µM for the human platelet and rabbit reticulocyte enzymes, respectively); reduces A23187-induced TXB2 and LTB4 production in human PBMCs (IC50s = 0.01 and 0.07 µM, respectively) and decreases epinephrine-induced platelet aggregation in human PRP (IC50 = 0.045 µM); inhibits paw swelling in a rat model of adjuvant-induced arthritis (ED50 = 3.5 mg/kg)
Size1 mg
Concentrationn/a
Applicationsn/a
Other NamesORF 20485|RWJ 20485
Gene, Accession, CAS #CAS: 103475-41-8
Catalog #34849-1
Price$37.00
Order / More InfoTepoxalin from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com

http://www.caymanchem.com

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