CPYPP from CAYMAN CHEMICAL COMPANY
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| Product Name | CPYPP |
| Description | An inhibitor of DOCK2 (IC50 = 22.8 µM for its GEF activity), DOCK5, and DOCK180; selective for these DOCKs over DOCK9; prevents chemokine-induced Rac activation in T and B cells at 100 µM; reduces migration of T cells to peripheral lymph nodes in mice at 5 mg/animal following adoptive transfer of spleen cells from knock-in mice expressing GFP-tagged DOCK2; reduces MPO activity in lung tissue, LPS-induced cytokine release in serum, and lung injury severity in a mouse model of endotoxemia-induced acute lung injury at 250 mg/kg |
| Size | 50 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 1413941-71-5 1413941-83-9 1426543-36-3 DOCK-2 5 9 180 DOCKA DOCKD Lipopolysaccharide |
| Gene, Accession, CAS # | CAS: 310460-39-0 |
| Catalog # | 17386-50 |
| Price | $570.00 |
| Order / More Info | CPYPP from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY