TC 14012 (hydrochloride) from CAYMAN CHEMICAL COMPANY
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| Product Name | TC 14012 (hydrochloride) |
| Description | A CXCR4 antagonist (IC50 = 2.9 nM) and CXCR7 agonist; induces β-arrestin recruitment in HEK293T cells expressing CXCR7 (EC50 = 350 nM); reduces the cytopathic effect of HIV in infected MT-4 cells (EC50 = 0.4 nM); inhibits HIV entry in vitro in a CXCR4-dependent manner (IC50 = 19.3 nM); inhibits CXCL12-induced migration in MDA-MB-231 cells and HUVECs from 10-1,000 nM; decreases infarct size in a mouse model of LAD coronary artery ligation-induced acute myocardial infarction at 10 mg/kg |
| Size | 1 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | H-Arg-Arg-Nal-Cys-Tyr-Cit-Lys-D-Cit-Pro-Tyr-Arg-Cit-Cys-Arg-NH2 |
| Gene, Accession, CAS # | n/a |
| Catalog # | 38140-1 |
| Price | $282.00 |
| Order / More Info | TC 14012 (hydrochloride) from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY