NSC 23925 from CAYMAN CHEMICAL COMPANY

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Product NameNSC 23925
DescriptionAn inhibitor of P-gp; selectively reverses multidrug resistance mediated by P-gp over MRP1- and BCRP-mediated multidrug resistance; resensitizes SKOV3TR and OVCAR-8TR cells to paclitaxel; reverses P-gp efflux, increasing the intracellular accumulation of P-gp substrates in multidrug resistant SKOV3TR and OVCAR-8TR cells; prevents paclitaxel-induced overexpression of MDR1 and P-gp protein level increases in OVCAR-8 cells; prevents the development of paclitaxel-induced multidrug resistance in a SKOV3 mouse xenograft model at 50 mg/kg per day in combination with paclitaxel
Size1 mg
Concentrationn/a
Applicationsn/a
Other Names19287-55-9 NSC23925 multi-drug MRP-1 ABCC-1 SKOV-3 OVCAR8 MDR-1 PgP
Gene, Accession, CAS #CAS: 858474-14-3
Catalog #21947-1
Price$36.00
Order / More InfoNSC 23925 from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com

http://www.caymanchem.com

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