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Product Name | Nitisinone |
Description | An inhibitor of HPPD; increases urinary levels of HPPA and HPLA in rats at 10 mg/kg; prevents the neonatal lethality of FAH deficiency in mice when administered to pregnant dams at 3 mg/kg; exhibits hepatoprotective effects in FAH-/- mice, such as prevention of increases in plasma levels of AST and conjugated bilirubin, when administration is continued following birth at 1 mg/kg; decreases urinary excretion of homogentisate and increases urinary excretion of HPPA, HPLA, and 4-hydroxyphenylacetate in a mouse model of ethylnitrosourea-induced alkaptonuria at 100 µg |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | NTBC|SC-0735 |
Gene, Accession, CAS # | CAS: 104206-65-7 |
Catalog # | 17924-50 |
Price | $32.00 |
Order / More Info | Nitisinone from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |