MC70 from CAYMAN CHEMICAL COMPANY
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| Product Name | MC70 |
| Description | A P-gp inhibitor; inhibits the efflux of [3H]vinblastine by ABCB1 in Caco-2 colon cancer cells (EC50 = 0.05 µM); inhibits the efflux of rhodamine-123 and calcein-AM by BCRP and MRP1 in MDCK cells (EC50s = 73 and 9.3 µM, respectively); enhances growth inhibition of MCF-7/ADR breast cancer cells at 2 or 20 µM when used in combination with doxorubicin in vitro, but does not alter the effectiveness of doxorubicin on growth inhibition in Caco-2 cells; increases phosphorylation of p38 and JNK in Caco-2 cells and MCF-7/ADR cells when used at a concentration of 20 µM |
| Size | 1 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | Pgp ABCB-1 Caco2 MDR-1 MRP-1 glyco-protein 3-H MC-70 MCF-7 p-38 multi-drug MCF7 |
| Gene, Accession, CAS # | CAS: 1031367-64-2 |
| Catalog # | 21330-1 |
| Price | $57.00 |
| Order / More Info | MC70 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY