CP 31,398 (hydrochloride) from CAYMAN CHEMICAL COMPANY
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| Product Name | CP 31,398 (hydrochloride) |
| Description | A p53 stabilizing agent; increases active mutant p53 and p53 reporter gene expression without increasing total protein levels of p53 in H1299 lung cancer cells transfected with mutant p53; is cytotoxic to a panel of 12 human glioma cell lines expressing wild-type or mutant p53 (EC50s = 11.2-22.2 µM); decreases tumor growth in an A375.S2 melanoma mouse xenograft model and completely inhibits tumor growth in a DLD-1 colon cancer mouse xenograft model at 100 mg/kg; dietary administration suppresses lung adenocarcinoma formation in a mouse model of tobacco carcinogen-induced lung adenoma and adenocarcinoma formation at 50 and 100 ppm, |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 259199-65-0 CP-31398 CP31398 p-53 H-1299 A375S2 DLD1 WT |
| Gene, Accession, CAS # | CAS: 1217195-61-3 |
| Catalog # | 27455-10 |
| Price | $119.00 |
| Order / More Info | CP 31,398 (hydrochloride) from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY