Edit |   |
---|---|
Product Name | Emavusertib |
Description | An IRAK4 inhibitor (IC50 = 31.7 nM); selective for IRAK4 over FLT3, Cdk2, Aurora A kinase, GSK3β, and MUSK at 1 µM; inhibits TLR2-, TLR5-, or IL-1R-mediated IL-6 release in isolated human whole blood (IC50s = 989, 696, and 1,375 nM, respectively); reduces tumor volume in an OCI-Ly3 DLBCL mouse xenograft model from 25-200 mg/kg |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | CA-4948 |
Gene, Accession, CAS # | CAS: 1801344-14-8 |
Catalog # | 36845-5 |
Price | $107.00 |
Order / More Info | Emavusertib from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |