Zardaverine from CAYMAN CHEMICAL COMPANY
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| Product Name | Zardaverine |
| Description | A dual inhibitor of PDE3 and PDE4 (IC50s = 0.617 and 1.738 µM, respectively, for the rat cardiac ventricle enzymes); selective for PDE3 and PDE4 over PDE1B, PDE2, and PDE5 (IC50s = >138 µM for all); inhibits aggregation of human platelets induced by ADP, PAF, collagen, arachidonic acid, or PGE1 and ADP (IC50s = 1.5-16.2 µM); inhibits zymosan-induced superoxide anion release from human PMNs (IC50 = 0.4 µM); decreases lung resistance and increases dynamic compliance in a rat model of acetylcholine-induced bronchospasm at 10 µmol/kg; decreases the viability of HeLa, COLO 741, NCI H2122, and A2058 cells (IC50s = 0.032, 0.027, 0.26, and 0.13 µM, respectively) |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | PDE-3 3A 4 1B 2 5 E PGE 1 COLO741 H 2122 A 2058 |
| Gene, Accession, CAS # | CAS: 101975-10-4 |
| Catalog # | 29685-5 |
| Price | $100.00 |
| Order / More Info | Zardaverine from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY