ZZW-115 from CAYMAN CHEMICAL COMPANY
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| Product Name | ZZW-115 |
| Description | A NUPR1 inhibitor; binds to NUPR1 (Kd = 2.1 µM) in a cell-free assay; cytotoxic against a panel of 11 pancreatic ductal adenocarcinoma cell lines (IC50s = 0.84-4.93 µM), as well as against a panel of 16 additional cancer cell lines, including glioblastoma, lymphoma, and leukemia cells (IC50s =0.25-7.75 µM); induces apoptosis and necrosis in MiaPaCa-2, LIPC, Foie8b, 02-063, and HN14 pancreatic cancer cells at 3 and 5 µM; induces ROS accumulation, lipid peroxidation, and ferroptosis in MiaPaCa-2 cells; reduces tumor growth in a MiaPaCa-2 mouse xenograft model at 1, 2.5, or 5 mg/kg |
| Size | 1 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | ZZW115 NUPR-1 MiaPaCa2 Mia-PaCa2 |
| Gene, Accession, CAS # | CAS: 10122-45-9 |
| Catalog # | 34974-1 |
| Price | $76.00 |
| Order / More Info | ZZW-115 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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