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Product Name | LY2109761 |
Description | A small molecule inhibitor of the TGF-β receptor type 1/type II kinases (IC50 = 69 nM); used to study the role of TGF-β signaling in tumor cell migration and metastasis; disrupts Smad-2 phosphorylation, an immediate downstream target of the kinase activity |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | inhibitors inhibits inhibitions TGF-β receptors types 1 kinases TGF-βR1 transforming growths factor-β cancers hepatocellular carcinomas Smad-2 signals transduction HCC dual Lys 2157299 LY-2157299 TGFs inflammatory cytokines signaling proangiogenic genes ID1 fibroblasts TGF-b TGF-.beta. TGF-beta beta .beta. b β I II ones two tumors metastasis Smad-two cells migrations |
Gene, Accession, CAS # | CAS: 700874-71-1 |
Catalog # | 15409-1 |
Price | $44.00 |
Order / More Info | LY2109761 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |