NSC 185058 from CAYMAN CHEMICAL COMPANY
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| Product Name | NSC 185058 |
| Description | An inhibitor of ATG4B; inhibits ATG4B cleavage of LC3B-GST (IC50 = 51 µM) and reduces LC3B lipidation induced by starvation in Saos-2 cells; reduces starvation-induced autophagy and prevents autophagic vacuole formation in Saos-2 and MDA-MB-468 cells (100 µM); decreases autophagy in vivo in mouse liver, inhibits tumor growth in mouse xenograft model, and decreases the number of autophagic vacuoles in osteosarcoma tumors (100 mg/kg) |
| Size | 1 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | NSC185058 ATG-4B LC-3B LC38GST Saos2 MDAMB468 RPS-6 |
| Gene, Accession, CAS # | CAS: 39122-38-8 |
| Catalog # | 23957-1 |
| Price | $57.00 |
| Order / More Info | NSC 185058 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
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