NMS-P715 from CAYMAN CHEMICAL COMPANY

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Product NameNMS-P715
DescriptionAn Mps1/TTK inhibitor (IC50 = 0.182 µM); selective for Mps1/TTK over a panel of 59 additional kinases (IC50s = >5 µM for all); accelerates mitosis, reducing the length of mitosis by approximately 3-fold, in U2OS cells; induces aneuploidy and apoptosis in A2780 ovarian cancer cells at 1 µM, as well as inhibits proliferation in a panel of 127 cancer cell lines (IC50s = 0.192-10 µM); reduces tumor growth in an A2780 mouse xenograft model at 90 mg/kg per day
Size5 mg
Concentrationn/a
Applicationsn/a
Other NamesNMSP715 Mps 1 A 2780
Gene, Accession, CAS #CAS: 1202055-32-0
Catalog #31613-5
Price$231.00
Order / More InfoNMS-P715 from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com

http://www.caymanchem.com

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