CUDC-305 from CAYMAN CHEMICAL COMPANY
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| Product Name | CUDC-305 |
| Description | An Hsp90 inhibitor; binds to Hspα and Hspβ (IC50s = 100 and 103 nM, respectively) and Hsp90 isolated from erlotinib-resistant NSCLC cells (IC50 = 70 nM); inhibits proliferation of 40 human cancer cell lines (IC50s = 0.04-0.9 µM); dose-dependently reduces tumor growth in a U87MG glioblastoma mouse xenograft model at 40-160 mg/kg; prolongs survival in a U87MG mouse orthotopic model at 160 mg/kg |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | CUDC305 Debio0932 Hsp-90 90α 90β BT474 ERK-1 ERK2 U-87MG U87-MG Debio 0932 U-87-MG |
| Gene, Accession, CAS # | CAS: 1061318-81-7 |
| Catalog # | 24683-5 |
| Price | $208.00 |
| Order / More Info | CUDC-305 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY