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Product Name | LL-37 (13-37) (human) (trifluoroacetate salt) |
Description | An anticancer peptide fragment of LL-37; inhibits the ATPase activity of ABCG2 at 1 µM; induces cytotoxicity in wild-type SW620 cells and SW620 cells overexpressing P-gp (IC50s = 25.5 and 27.3 µM, respectively), as well as wild-type MCF-7 cells, MCF-7 cells overexpressing ABCG2, and MCF-7 cells overexpressing MRP1 (IC50s = 33.1, 31.8, and 31.1 µM, respectively); potentiates mitoxantrone-induced cytotoxicity in MCF-7 and HEK293 cells overexpressing ABCG2 at 5 or 10 µM; decreases mitoxantrone drug efflux by, and increases mitoxantrone levels in, MCF-7 cells overexpressing ABCG2 at 10, 20, or 40 µM |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | CAP-18|Cathelicidin|FALL-39|hCAP-18|IG-25|LL-13|LL-25 |
Gene, Accession, CAS # | n/a |
Catalog # | 36949-5 |
Price | $146.00 |
Order / More Info | LL-37 (13-37) (human) (trifluoroacetate salt) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |