ARN14686 from CAYMAN CHEMICAL COMPANY
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| Product Name | ARN14686 |
| Description | An affinity probe for NAAA using click chemistry; inhibits the hydrolysis of the NAAA substrate PAMCA in HEK293 cells (IC50s = 6 and 13 nM for human and rat recombinant enzymes, respectively); selective for NAAA over acid ceramidase (IC50 = 1,200 nM for the rat enzyme); labels NAAA in HEK293 cells; labels NAAA in rat lung lysosomal fractions in vitro at 1 and 10 µM; detects NAAA in lung lysosomal fractions following a 10 mg/kg, i.v. dose in rats; has been used to determine that catalytically active NAAA is present in inflamed rat paw in a complete Freund's adjuvant model of inflammation at 3 mg/kg |
| Size | 5 mg |
| Concentration | n/a |
| Applications | Click Chemistry |
| Other Names | Click Tag™ ARN14686 |
| Gene, Accession, CAS # | CAS: 1628345-10-7 |
| Catalog # | 24261-5 |
| Price | $216.00 |
| Order / More Info | ARN14686 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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