CAY17c from CAYMAN CHEMICAL COMPANY
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| Product Name | CAY17c |
| Description | An inhibitor of BRD4 and class I and class IIb HDACs; inhibits BRD4 (IC50 = 0.71 µM), as well as class I HDACs (IC50s = 0.046, 0.058, 0.075, and 0.167 µM for HDAC1, -2, -3, and -8, respectively) and class IIb HDACs (IC50s = 0.073 and 0.923 µM for HDAC6 and HDAC10, respectively); selective for these enzymes over BRD2, -3, and -T (IC50s = >20 µM for all), as well as over HDAC4, -5, -7, -9, and -11 (IC50s = >10 µM for all); inhibits proliferation of HCT116, SW620, and DLD-1 cells (IC50s = 0.45, 1.78, and 2.11 µM, respectively); induces apoptosis and autophagy in HCT116 cells; reduces tumor growth in an HCT116 mouse xenograft model at 15 and 30 mg/kg |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | CAY 17c BRD-2 BRD3 BRD-3 BRD-4 HDAC-10 4 HCT-116 SW-620 DLD1 |
| Gene, Accession, CAS # | CAS: 2414373-11-6 |
| Catalog # | 31077-5 |
| Price | $433.00 |
| Order / More Info | CAY17c from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY