PS-1145 from CAYMAN CHEMICAL COMPANY
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| Product Name | PS-1145 |
| Description | An IKKβ inhibitor (IC50 = 88 nM); selectively inhibits IKKβ over a panel of 14 kinases (IC50s = >100 nM for all); inhibits the IKK complex (IC50 = 100 nM); inhibits the proliferation of MM.1S, U266, and RPMI-8226 cells at 1.5-50 µM; inhibits TNF-α-induced activation of NF-κB in MM.1S cells; inhibits RANKL-induced osteoclast differentiation of RAW 264.7 cells into osteoclasts at 5 and 10 µM; inhibits RANKL-induced phosphorylation of IκBα, ERK, and JNK in RAW 264.7 cells at 10 µM |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | IKK Inhibitor X |
| Gene, Accession, CAS # | CAS: 431898-65-6 |
| Catalog # | 14862-5 |
| Price | $130 |
| Order / More Info | PS-1145 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY