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Product Name | Vosaroxin |
Description | A topoisomerase II inhibitor; induces relaxation of supercoiled DNA (IC50 = 3.2 µg/ml); induces DNA double-strand breaks in CCRF-CEM cells and cell cycle arrest at the G2 phase in A549 cells in a concentration-dependent manner; inhibits proliferation in a panel of 15 cancer cell lines, including cancer cells resistant to doxorubicin, etoposide, or cisplatin (IC50s = 0.04-1.15 µM); inhibits tumor growth in multidrug-resistant SBC-3/ETP or PC-14/CDDP mouse xenograft models at 20 mg/kg |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | SNS-595|Voreloxin |
Gene, Accession, CAS # | CAS: 175414-77-4 |
Catalog # | 30614-10 |
Price | $286.00 |
Order / More Info | Vosaroxin from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |