GSK3368715 (hydrochloride) from CAYMAN CHEMICAL COMPANY
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| Product Name | GSK3368715 (hydrochloride) |
| Description | An inhibitor of type I PRMTs (IC50s = 3.1, 162, 38, 4.7, and 39 nM for PRMT1, 3, 4, 6, and 8, respectively); selective for type I PRMTs over PRMT5, 7, and 9 (IC50s = >20,408, >40,000, and >15,000 nM, respectively), as well as 20 additional methyltransferases and a panel of ion channels, receptors, and transporters at 10 µM; inhibits the growth of patient-derived DLBCL cells at 5 µM; reduces tumor volume in Toledo and BxPC-3 mouse xenograft models from 9.375-150 mg/kg; reduces tumor growth in ACHN and MDA-MB-468 mouse xenograft models and a pancreatic adenocarcinoma PDX mouse model at 150 and 300 mg/kg, respectively |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 1629013-22-4 1628925-77-8 GSK-3368715 PRMT-1 5 7 9 Bx-PC3 BxPC3 MDAMB468 MDAMB-468 MDA-MB468 |
| Gene, Accession, CAS # | CAS: 2227587-25-7 |
| Catalog # | 34886-10 |
| Price | $602.00 |
| Order / More Info | GSK3368715 (hydrochloride) from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY