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Product Name | KIN1148 |
Description | An IRF3 activator and adjuvant; increases the mRNA expression of the genes encoding ISG54 and OASL in PH5CH8 cells and increases CXCL10 production in phorbol 12-myristate 13-acetate-differentiated THP-1 monocytes at 10 µM; immunization with a vaccine in combination with KIN1148 increases blood IgG, neutralizing, and hemagglutinin antibody titers, decreases PFUs in the lungs and lung-draining lymph nodes, and increases the survival percentage of mice infected with a lethal dose of influenza virus when used as an adjuvant |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 2248612-50-0 KIN-1148 IRF-3 ISG-54 CXC-Motif CXCL-10 THP1 |
Gene, Accession, CAS # | CAS: 1428729-56-9 |
Catalog # | 38980-10 |
Price | $536.00 |
Order / More Info | KIN1148 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |