Edit |   |
---|---|
Product Name | Asapiprant |
Description | An antagonist of DP1 (Ki = 0.44 nM); selective for DP1 over DP2, as well as the TXA2, PGI2, and PGE1-4 receptors (Kis = >5,000, >4,800, >6,300, 120->6,600 nM, respectively); reduces PGD2-induced increases in nasal resistance in a guinea model of allergic rhinitis at 1 and 3 mg/kg; reduces nasal secretion at 3 and 30 mg/kg and antigen-induced cell infiltration at 3 and 10 mg/kg in a guinea pig model of ovalbumin-induced allergic rhinitis; decreases airway hyperresponsiveness, inflammatory cell infiltration in BALF, and mucin production in a rat model of ovalbumin-induced asthma |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | S-555739 |
Gene, Accession, CAS # | CAS: 932372-01-5 |
Catalog # | 30008-5 |
Price | $201.00 |
Order / More Info | Asapiprant from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |