SGC-iMLLT from CAYMAN CHEMICAL COMPANY

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Product NameSGC-iMLLT
DescriptionAn inhibitor of the YEATS domain-containing proteins MLLT1 and MLLT3; binds to the MLLT1 YEATS1 and MLLT3 YEATS3 domains (Kds = 129 and 77 nM, respectively); selective for YEATS1 and -3 over YEATS2 and -4 (IC50s = >10 µM), as well as a panel of 48 bromodomains at 50 µM; inhibits histone H3.3 interactions with MLLT3 (IC50 = 400 nM in a reporter assay); decreases expression of MYC and DDN in MV-4-11 leukemia cells at 1 µM
Size1 mg
Concentrationn/a
Applicationsn/a
Other NamesMLLT-1 3 MLLT1YEATS MLLT3YEATS H-3.3 MV411 MV4-11 4 bromo domains
Gene, Accession, CAS #CAS: 2255338-25-9
Catalog #28113-1
Price$37.00
Order / More InfoSGC-iMLLT from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com

http://www.caymanchem.com

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