AS-605240 from CAYMAN CHEMICAL COMPANY
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| Product Name | AS-605240 |
| Description | A potent inhibitor of PI3Kγ; inhibits human recombinant PI3Kγ, α, β, and δ in an ATP-competitive manner (IC50s = 8, 60, 270, and 300 nM, respectively); inhibits C5a-mediated phosphorylation of protein kinase B in RAW 264 cells (IC50 = 90 nM); suppresses joint inflammation in mouse models of rheumatoid arthritis; reduces RANTES-induced peritoneal neutrophil recruitment in a mouse model of leukocyte chemotaxis (ED50 = 9.1 mg/kg) |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | phosphoinositide 3-kinases PI3-kinase PI3-K PI3K phosphoinositide phosphatidylinositols inibitors inflammation arthritis rheumatoid peritonitis neutrophils recruitment as605240 |
| Gene, Accession, CAS # | CAS: 648450-29-7 |
| Catalog # | 10007707-10 |
| Price | $93.00 |
| Order / More Info | AS-605240 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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