R162 from CAYMAN CHEMICAL COMPANY
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| Product Name | R162 |
| Description | A GDH1 inhibitor (IC50 = 23 µM); decreases intracellular fumarate levels and increases mitochondrial ROS production in human H1299 lung and MDA-MB-231 breast cancer cells; inhibits proliferation in a panel of human cancer cell lines but not normal human cells from 10-40 µM; reduces tumor growth and intratumoral GDH1 activity in an H1299 mouse xenograft model at 20 mg/kg; reduces liver metastasis in a liver kinase B1-deficient lung cancer PDX mouse model |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | R 162 GDH 1 intra-cellular H 1299 MDAMB231 MDAMB-231 MDA-MB231 Ha CaT MRC5 |
| Gene, Accession, CAS # | CAS: 64302-87-0 |
| Catalog # | 30922-5 |
| Price | $51 |
| Order / More Info | R162 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY