NLRP3i from CAYMAN CHEMICAL COMPANY
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| Product Name | NLRP3i |
| Description | An NLRP3 inflammasome inhibitor; selective for NLRP3 over NLRP4 and AIM2 inflammasomes at 400 µM; inhibits LPS-induced IL-1β release and ASC oligomerization in J774A.1 mouse macrophages; reduces infarct size and cardiac levels of troponin I in a mouse model of acute myocardial infarction at 100 mg/kg; reduces peritoneal leukocyte infiltration in a mouse model of zymosan A-induced peritonitis; decreases plasma IL-18 levels and reduces systolic and diastolic dysfunction in a mouse model of Western diet-induced obesity at 100 mg/kg |
| Size | 1 g |
| Concentration | n/a |
| Applications | n/a |
| Other Names | NLRP 3 4 i AIM 2 IL1β IL18 J774 A.1 |
| Gene, Accession, CAS # | CAS: 16673-34-0 |
| Catalog # | 30895-1 |
| Price | $62.00 |
| Order / More Info | NLRP3i from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY