AS-2863619 from CAYMAN CHEMICAL COMPANY
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| Product Name | AS-2863619 |
| Description | A dual inhibitor of Cdk8 and Cdk19 (IC50s = 0.6 and 4.3 nM, respectively); induces Foxp3 expression in isolated mouse naive T cells at 1 µM alone or synergistically with TGF-β; decreases ear edema and induces production of Foxp3+ Tregs in mice at 30 mg/kg; reduces disease severity in a mouse model of EAE |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 2241300-50-3 AS2863619 Cdk 8 19 Foxp-3 + TGFβ auto immune |
| Gene, Accession, CAS # | CAS: 2241300-51-4 |
| Catalog # | 30976-5 |
| Price | $435.00 |
| Order / More Info | AS-2863619 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
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http://www.caymanchem.com
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