Dienogest from CAYMAN CHEMICAL COMPANY
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| Product Name | Dienogest |
| Description | A synthetic progestin and PR agonist (EC50s = 3.4-10.5 nM in transactivation assays); selective for PR over ERα and ERβ, as well as glucocorticoid, and mineralocorticoid receptors (EC50s = >3,000 nM for all), as well as SHBG and CBG (IC50s = 900-950 and 7,970 nM, respectively, in radioligand binding assays); inhibits dihydrotestosterone-induced transactivation of the androgen receptor (EC50s = 420.6-775 nM); reduces lesion formation in a rat model of endometriosis at 0.1, 0.3, and 1 mg/kg per day for 21 days orally; reduces 17β-estradiol benzoate-dependent tumor growth in an MCF-7 ovariectomized mouse xenograft model at 0.1 and 1 mg/kg per day for 28 days |
| Size | 50 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | STS 557 |
| Gene, Accession, CAS # | CAS: 65928-58-7 |
| Catalog # | 21257-50 |
| Price | $384.00 |
| Order / More Info | Dienogest from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY