RS 17053 (hydrochloride) from CAYMAN CHEMICAL COMPANY
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| Product Name | RS 17053 (hydrochloride) |
| Description | An α1A-AR antagonist; selectively binds to the α1A-AR (Ki = 2.5 nM) over α1B-and α1D-ARs (Kis = 50 and 79 nM, respectively); inhibits norepinephrine-induced contractions in isolated rat kidney and mesenteric arteries (pA2s = 9.8 and 9.9, respectively) and, to a lesser extent, in isolated rat aortic rings and human lower urinary tract tissue (pA2s = 7.7 and 7.3, respectively); inhibits phenylephrine-induced increases in MAP in normotensive and spontaneously hypertensive rats (ED50s = 528 and 533 µg/kg, respectively) |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 169506-22-3 RS17053 α1AAR α1DAR α1BAR p-A2 pA-2 |
| Gene, Accession, CAS # | CAS: 169505-93-5 |
| Catalog # | 33548-5 |
| Price | $110.00 |
| Order / More Info | RS 17053 (hydrochloride) from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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