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Product Name | Tranylcypromine (hydrochloride) |
Description | An irreversible, mechanism-based inhibitor of LSD1 (IC50 = 20.7 µM); irreversibly inhibits MAO-A and MAO-B (IC50s = 2.3 and 0.95 µM, respectively); PCPA inhibits nucleosomal demethylation of H3K4 (IC50 = <2 µM); induces EpiSCs to convert to more undifferentiated state but requires inhibitors of ALK5, MEK, FGFR, and GSK3 for full conversion to pluripotent mESCs; decreases proliferation of neural progenitors in the hippocampal dentate gyrus in adult mice at 10 mg/kg for ten days; decreases the time juvenile rats spend immobile in the forced swim test at 0.4-10 mg/kg |
Size | 100 mg |
Concentration | n/a |
Applications | n/a |
Other Names | trans-2-Phenylcyclopropylamine|2-PCPA |
Gene, Accession, CAS # | CAS: 1986-47-6 |
Catalog # | 10010494-100 |
Price | $25.00 |
Order / More Info | Tranylcypromine (hydrochloride) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |