9(Z),11(E),13(E)-Octadecatrienoic Acid from CAYMAN CHEMICAL COMPANY
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| Product Name | 9(Z),11(E),13(E)-Octadecatrienoic Acid |
| Description | α-ESA is a conjugated PUFA commonly found in plant seed oil. This fatty acid accounts for about 60% of the total fatty acid composition of bitter gourd seed oil and about 70% in tung oil.{14176} α-ESA is metabolized and converted to conjugated linoleic acid (9Z,11E-CLA) in rats.{14175} It has shown potential as a tumor growth suppressor. In colon cancer Caco-2 cells, α-ESA induced apoptosis through up-regulation of GADD45, p53, and PPARγ.{14176} In DLD-1 cells supplemented with α-ESA, apoptosis was induced via lipid peroxidation with an EC50 of 20 µM.{14175} It also inhibits DNA polymerases and topoisomerases with IC50s ranging from ~5-20 µM for different isoforms of the enzymes.{14174} |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | LAF 237|α-Eleostearic Acid|α-ESA |
| Gene, Accession, CAS # | CAS: 506-23-0 |
| Catalog # | 10008349-10 |
| Price | $437.00 |
| Order / More Info | 9(Z),11(E),13(E)-Octadecatrienoic Acid from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY