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Product Name | Tenapanor (hydrochloride) |
Description | An orally bioavailable NHE-3 inhibitor (IC50 = 10 nM for the recombinant rat protein); inhibits intestinal fluid absorption in mouse jejunum, but not distal colon, in a closed intestine loop assay at 10 µM; lowers both the sodium and phosphate urinary-to-dietary ratio in a dose-dependent manner in rats; reverses loperamide-induced decreases in stool pellet numbers and water content and prevents loperamide-induced constipation in mice at 5 mg/kg |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | AZD 1722 |
Gene, Accession, CAS # | CAS: 1234365-97-9 |
Catalog # | 32875-10 |
Price | $188.00 |
Order / More Info | Tenapanor (hydrochloride) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |