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Product Name | Zaprinast |
Description | A cGMP phosphodiesterase inhibitor (IC50s = 0.5-0.76 and 0.15 µM for PDE5 and PDE6, respectively); selective for PDE5 and PDE6 over PDE9, PDE10, and PDE11 (IC50s = 35, 22, and 11-33 µM, respectively); enhances the vasodilatory effects of NO in a range of vascular tissues by prolonging the cGMP-mediated activation of cGMP-dependent protein kinase; activates both rat and human GPR35 (EC50s = 16 nM and 0.84 µM, respectively) |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 2-(o-Propoxyphenyl)-8-azapurin-6-one|M&B 22,948 |
Gene, Accession, CAS # | CAS: 37762-06-4 |
Catalog # | 10010421-10 |
Price | $28.00 |
Order / More Info | Zaprinast from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |