Efaproxiral from CAYMAN CHEMICAL COMPANY
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| Product Name | Efaproxiral |
| Description | An allosteric Hb modifier that reduces the affinity of Hb for oxygen, increasing the diffusion of oxygen from blood to tissue; increases p50 from 26.75 to 38.63 mm Hg and decreases the percent Hb-O2 saturation from 48 to 33.8% at a pO2 of 26 mm Hg in isolated human whole blood at 1.75 mM; increases tumor pO2 from 5.2 to 13.1 mm Hg 30 minutes after administration in a RIF-1 mouse fibrosarcoma flank tumor model at 150 mg/kg; enhances radiation-induced cytotoxicity in EMT6 mouse breast cancer cells grown under hypoxic conditions at 100 µM; increases radiosensitization and inhibits tumor growth in a hypoxic Lewis lung tumor mouse model at 100 mg/kg; increases the running capacity of normal mice and mice with LCA ligation-induced MI at 150 mg/kg |
| Size | 100 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | RSR 13 |
| Gene, Accession, CAS # | CAS: 131179-95-8 |
| Catalog # | 28294-100 |
| Price | $68.00 |
| Order / More Info | Efaproxiral from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY