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Product Name | ARS1620 |
Description | A covalent inhibitor of K-RASG12C (IC50 = G12C (IC50s = 150 nM) over various cells expressing wild-type K-RAS (IC50s = >10 µM); induces tumor regression in a MIA-PaCa2 mouse xenograft model at 200 mg/kg; decreases tumor volume in K-RASG12C-expressing PDX mouse models |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | KRASG12C ARS-1620 KRAS-G12C G-12C H-358 MIAPaCa2 MIAPaCa-2 LU-65 H-441 A-549 HCT-116 KRASG12D G12D WT |
Gene, Accession, CAS # | CAS: 1698055-85-4 |
Catalog # | 27915-5 |
Price | $351.00 |
Order / More Info | ARS1620 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |